Abstract: Background: Nicotine consumption has been linked to many diseases and the negative effects especially on the brain as concerned to memory and emotion. Psidium guajava (Guava) is a medicinal plant with a long history of use for its pharmacologic properties. Aim: This study aims at investigating the ameliorative effects of Psidium guajava aqueous leaf extract (PGALE) on the histology of the hippocampus in nicotine-induced neurotoxicity in wistar rats. Methodology: Thirty (30) adult male wistar rats (150-200g) were divided into six (6) groups (n=5). Group A (control group) received only food and water ad libitum. Group B (Untreated) was injected subcutaneously with 0.1ml of 1% nicotine every 48 hours till the end of the experiment. Group C, D, E and F received same but were treated daily with 200, 400, 600mg/kg of PGALE and 100mg/kg of Vitamin E respectively. The experiment lasted 28 days. The animals were sacrificed 24 hours after last treatment under ketamine (100mg/ml) as anesthesia. Neatly harvested brains were fixed for histological studies stained with H&E. Results: Nicotine injections caused severe neurodegenerative injuries on the histology of the hippocampus characterized by marked degeneration of neurons, cytoplasmic vacuolations, decreased cellular population and pyknosis of pyramidal cells in untreated group. Treatment with the PGALE and Vitamin E ameliorated these effects as they demonstrated only mild to moderate degenerative injuries relative to the untreated groups. Conclusion: Psidium Guajava demonstrated a strong dose-dependent ameliorative potential.

Keywords: Psidium Guajava, Neurotoxicity, Hippocampus, Nicotine.

Title: AMELIORATIVE POTENTIALS OF PSIDIUM GUAJAVA (GUAVA) AQUEOUS LEAF EXTRACT ON THE HISTOLOGY OF THE HIPPOCAMPUS IN RAT MODELS OF NICOTINE-INDUCED NEUROTOXICITY

Author: Christian Chiemeka Ozor, Chiamaka Victoria Belonw, Christian Ejuiwa Mba

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 112-116

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 31-December-2025

Abstract: Nursing practices in Asia are influenced by the diversified socio-economic settings, cultural environments, and healthcare facilities of the region. Japan and South Korea have high-income economies with enhanced nursing practices resulting from established healthcare systems, government financing, and formal nursing educational schemes. Low- and middle-income economies such as India, Indonesia, and the Philippines have healthcare disparities, restricted access to resources, and underdeveloped nursing education systems. This imbalance affects the position of nurses in healthcare provisions, their professional roles and society’s acknowledgement of them. Furthermore, government policy, cultural perception of healthcare, and access to medical technology greatly affect the nursing profession throughout Asia.

The research identifies the problems nurses encounter, such as shortages of personnel, poor training facilities, and different degrees of professional autonomy. Through a review of the literature and case studies, this study investigates the similarities and differences in nursing practices throughout the region. The research highlights the need for policy reforms, better education programs, and more investments in healthcare systems to improve nursing practices. Finally, the research emphasizes the necessity of a more uniform system of nursing education and professional development in Asia to provide quality healthcare services and equal access to medical care for all populations.

Keywords:  Nursing Global Trends, Nursing in Healthcare, Nursing Issues, Nursing Practices.

Title: Issues and Trends in Nursing Practices Asian Countries: Collective Review

Author: Dr. James Ryan Reblando

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 100-110

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 15-December-2025

Abstract: Abnormal corollary discharge has been implicated in schizophrenia and manifests as reduced suppression of auditory evoked responses during self-generated sounds. We investigate whether deep convolutional neural networks (CNNs) trained on EEG from a basic button–tone task can detect schizophrenia at the single-trial/subject level. We analyzed EEG from 81 participants (schizophrenia and healthy controls; combined across a prior publication and a larger replication cohort) collected during three conditions: (1) button press generating a tone, (2) passive tone, and (3) button press without tone. Preprocessing included re-referencing to averaged earlobes, 0.1 Hz high-pass filtering, canonical correlation analysis for muscle/high-frequency noise removal, ICA artifact rejection, epoching, baseline correction, and interpolation of outlier channels/trials. We trained a 2D-CNN optimized with Adam where inputs comprised from up to 64 electrodes. On a held-out validation set, the model achieved accuracy = 0.6265 and val loss = 0.6455. From the confusion matrix, we obtained recall (schizophrenia) = 0.578, specificity = 0.640, precision = 0.308, and F1 = 0.402.

Keywords: Schizophrenia detection; EEG; Deep Learning; CNN.

Title: Schizophrenia Detection Using Convolutional Neural Networks on EEG Data

Author: Faezeh Norouzi, Fariba Ghasemi

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 93-99

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 24-November-2025

Abstract: This case study presents the nursing care management of a 66-year-old woman diagnosed with symptomatic cholelithiasis and treated with laparoscopic cholecystectomy. The purpose of the study was to apply theoretical knowledge to clinical practice through comprehensive assessment, identification of nursing needs, implementation of evidence-based interventions, and evaluation of patient outcomes. Orem’s Self-Care Deficit Theory guided the nursing approach, utilizing both partly compensatory and supportive-educative systems. Key postoperative issues included acute pain, risk of fluid and nutritional imbalance, and lack of disease-related knowledge. Targeted interventions such as pain management, hydration monitoring, dietary education, ambulation support, and health teaching were implemented to promote recovery and enhance self-care ability. Diversional therapies and individualized patient support further contributed to psychological comfort and coping. The patient demonstrated steady improvement, maintained stable vital signs, and was discharged with appropriate instructions regarding diet, activity, medication adherence, and follow-up care. This case study strengthened the application of holistic nursing practice, clinical judgment, and patient-centered education in managing cholelithiasis.

Keywords: nursing care management, symptomatic cholelithiasis, laparoscopic cholecystectomy. supportive-educative systems.

Title: A Case Study On Cholelithiasis

Author: Nofiah Dhabaan Alshammary

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 65-92

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 19-November-2025

Abstract: The Kenya Ministry of Health guidelines for HIV screening and testing recommend the use of facility-based point-of-care antibody-based rapid diagnostic tests. A positive HIV test is made using 3 consecutive reactive assays in a 3-test algorithm that ensures the maintenance of about 99% positive predictive value. However, false positive HIV tests have been reported in pregnancy, COVID-19, lymphomas, metastatic cancers, viral infections, and autoimmune diseases. Seropositive rheumatoid arthritis (RA) has been particularly associated with false positive HIV antibody tests due to a cross-reactivity of the autoantibodies to the rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) with the HIV-specific antigens. The result may lead to unnecessary treatment of patients with antiretroviral therapy (ARVs). In this study, we report the case of a 44-year-old Kenyan woman with poorly controlled seropositive RA in pregnancy whose repeat HIV test during labor was falsely positive, leading to her and her baby being inadvertently treated with ARVs. We point out the value of a cautious interpretation of a positive HIV test in this population, the need for confirmatory testing, and call for clear algorithms in managing false positive HIV tests in the Kenyan guidelines.

Keywords: HIV testing, false positive HIV test, seropositive RA, RF-positive, anti-CCP, Kenya.

Title: A False-Positive Repeat HIV Test during Labor in Poorly Controlled Seropositive Rheumatoid Arthritis in a Rural Kenyan Hospital

Author: Onyango C. Vonwicks, Kibet Peter, Fryda C. William  

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 61-64

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 04-November-2025

Abstract: Nowadays, Saudi Arabia is undergoing a magnificent health system transformation that involves the expansion of care, budget control and engaging private sectors in providing care. As nursing is the biggest part of potential workforce in any healthcare organization it is crucial to understand reasons behind nurses outflow from a single unit to another unit.Although nursing transfers between units would allow the organization to manage the shortage and it will also enhance nursing skills, yet, nurses’ request of transfer will affect the unit workflow and patient care. Adjusting to a new unit with different work routine and different patient population will increase the possibility of errors and increase the staff stress. Thus, effective management of these interdepartmental transfers is a must for overall hospital performance. For that, this study aims to explore reasons influencing nurses’ interdepartmental transfers. Furthermore, despite how frequent nurses are transferring to different departments, there is limited literature that comprehensively analyze the reasons and the impact of nurses’ interdepartmental transfers. Therefore, a recent thesis will assist to reveal any knowledge gap.

Keywords: “Nurses Burnout”, “Nurses Intention to leave”, “Nurses Job Satisfaction”, “Nurses Retention”, “Nurses Turnover”, “Nurses Work-Life Balance”, “Nursing Leadership”, “Nursing Payments”, “Nursing Shortage”, “Organizational Factors”, “Psychosocial Factors”, “Reasons Affecting Nurses’ transfers”.

Title: Reasons Influencing Nurses’ Interdepartmental Transfers in King Fahd Armed Forces Hospital

Author: Riham Bahanshal, Ghada M Hamoudah

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 43-60

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 29-October-2025

Abstract: Ischaemic Heart Disease (IHD) remains the leading cause of death and disability in Australia, posing a major public health and economic challenge. Affecting over 580,000 Australians and responsible for around 20,000 deaths annually, IHD accounts for more than $2 billion in healthcare costs each year. Its burden is influenced by socioeconomic inequalities, limited social support, and environmental factors, along with individual risks such as age, obesity, hypertension, and smoking. This paper examines the burden and determinants of IHD in Australia and assesses the applicability of the Chronic Care Model (CCM) in improving its prevention and management. Through its emphasis on patient self-management, coordinated care, and community engagement, the CCM provides an effective framework for enhancing health outcomes and reducing the overall impact of IHD.

Keywords: Ischaemic Heart Disease, Australia, Public Health, Risk Factors, Chronic Care Model, Cardiovascular Disease, Health Management.

Title: Burden of Ischaemic Heart Disease (IHD) in Australia

Author: ABDULAZIZ AL GHASEB

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 38-42

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 09-October-2025

Abstract: This study sought to evaluate the demographic distribution, perceptions of childhood vaccination, and their relationship with vaccination uptake among participants. Public attitudes toward vaccines are influenced by multiple factors, including past interactions with healthcare systems, cultural and religious beliefs, exposure to misinformation, and perceptions of vaccine safety and effectiveness. The dynamics surrounding these perceptions were further complicated by the COVID-19 pandemic, during which the spread of misinformation on social media significantly undermined public trust. A total of 810 participants were surveyed. Data on demographic variables, perception of childhood vaccination, and vaccination uptake were collected via interviewer-administered questionnaire and analysed using chi-square tests and odds ratios. Most participants were aged 30-39 years (34.3%), female (78%), and married (60.2%). Most had secondary education (55.1%) and were self-employed (40.2%). The perception of childhood vaccination was generally positive, with 66.2% agreeing that vaccines are important for protecting children from serious diseases. However, 55.1% disagreed that vaccines have more risks than benefits. The association between demographic variables and perception revealed significant differences based on gender (p=0.015), marital status (p<0.001), and education level (p=0.021). Participants with a poor perception of vaccination were almost twice as likely to have incomplete vaccination (OR=1.95, 95% CI: 1.4 – 2.6, p=0.0001). The study highlights the importance of addressing demographic factors in vaccination campaigns to improve perception and uptake of childhood vaccination. Efforts should focus on educating and engaging specific demographic groups to enhance vaccination coverage.

Keywords: Vaccination, Perception, Uptake, COVID-19, Bayelsa.

Title: CHILDHOOD VACCINATION UPTAKE AND PUBLIC PERCEPTION POST-COVID-19 IN BAYELSA STATE, NIGERIA

Author: Adelekun, Omobolanle Esther

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 29-37

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 29-September-2025

Abstract: Postpartum depression (PPD) is worldwide known as one of the most common complications of childbearing. It affects the health and wellbeing of many mothers, their infants, and their families. Globally, childbirth is a period of women’s life content an intense and strong emotion, both negative and positive and transition naturally health. This transition in a woman's life has been subjected to change in location.  This study aimed to investigate if maternal childbirth complications affect postpartum depression. A Searches were completed using PsycINFO, Medline and PubMed databases through the Saudi Digital library database. The eligibility criteria included: full text articles, researches in English language, researches which studied the relationship between maternal childbirth complications and occurrence of postpartum depression. All the included studies were critically appraised. After the selection process, 13 studies matching the inclusion criteria identified and were incorporated into the review. Results: The literature review content categorized into four themes: preterm labor; perineal injury; cesarean birth; postpartum hemorrhage and the most common among them was the cesarean birth.

Keywords: Impact, effect, delivery complications, childbirth complications, relationship, postpartum depression, women.

Title: Impact of Childbirth Complications on Postpartum Depression Occurrence: A scoping review

Author: Munayfah Musallam Alruwaili, Badriyah Musallam Alruwaili

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 23-28

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 29-September-2025

Abstract: This paper introduces a foundational concept for an innovative treatment method designed, by physiotherapist Papantonopoulos Konstantinos, specifically for individuals who are in a standing position and preparing to walk, with a particular focus on those who have sustained injuries from accidents. The primary objective of this proposed approach is to facilitate a swift recovery for these individuals following such traumatic events. Research has shown that achieving an upright posture, with minimal reliance on external support, can be advantageous and therapeutically effective, even in situations where there is a considerable loss of sensory and/or motor function. This method aims to improve rehabilitation outcomes by fostering independence and mobility among patients, ultimately enhancing their overall quality of life throughout the recovery journey.

Keywords: gait assistive training, motor deficit.

Title: Gait Assistive Integrated Training: Therapeutic program for the development of standing and preparation for walking, for people with motor deficits

Author: Papantonopoulos Konstantinos, Vaitsis Nikolaos

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 14-22

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 13-September-2025

Abstract: Skin-to-skin contact at birth is an evidence-based practice that promotes maternal-infant bonding, initiation of breastfeeding, and neonatal physiological stability. Although encouraged by global initiatives such as the Baby-Friendly Hospital Initiative (BFHI), routine adoption is still low. Nurses, as primary care providers in obstetric wards, play a major role in implementing SSC, yet their knowledge, attitudes, and practices (KAP) are generally problematic. Within the Saudi Arabian context, additional cultural elements, including modesty concerns and limited standardized protocols, compound practice. This article provides a literature review underpinning a pre-post quasi-experimental study to determine the effectiveness of a structured educational program in enhancing nurses' KAP regarding SSC. Sixteen recent studies were examined to determine the benefits of SSC, nurses' current competencies, systemic and cultural barriers, and the impact of educational interventions. Evidence shows that while the benefits of SSC are well known, nurses' knowledge and practice gaps occur alongside generally positive attitudes. The evidence substantiates education as the most effective and culturally flexible answer to these barriers. The review constructs a strong argument for the proposed intervention, foreseeing that targeted education will improve nurses' SSC competency and adherence, resulting in improved maternal-infant health outcomes for Saudi obstetric hospitals.

Keywords: Skin-to-Skin Contact, Nursing Education, Obstetrics, Saudi Arabia, Knowledge, Attitudes, Practices, Quasi-Experimental Study.

Title: Effectiveness of an Education Program on Nurses' Knowledge, Attitudes, and Practices Regarding Skin-to-Skin Contact in Obstetrics Departments: A Pre-Post Quasi-Experimental Study

Author: Tarfa Yasser Bakhashwain

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 7-13

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 10-September-2025

Abstract: Dysmenorrhea and premenstrual syndrome (PMS) are prevalent health concerns among young women globally, including in Saudi Arabia, where limited research has explored the impact of educational interventions on lifestyle modification to alleviate symptom severity. This literature review involved 20 studies, findings demonstrating the effectiveness of educational sessions focusing on diet, physical activity, and stress management in reducing dysmenorrhea and PMS symptoms. Cultural, social, and healthcare factors unique to Saudi Arabia may influence both the manifestation of these conditions and the success of lifestyle-based interventions. Smoking, dietary habits, physical inactivity, and sleep patterns have been identified as modifiable risk factors associated with dysmenorrhea and PMS in this population. The review underscores the need for culturally tailored research and targeted educational programs to improve symptom management and quality of life for Saudi women. Addressing these gaps is essential for developing effective healthcare strategies responsive to the sociocultural context of Saudi Arabia.

Keywords: Dysmenorrhea and premenstrual syndrome (PMS), educational interventions, lifestyle modification, educational sessions.

Title: Impact of Lifestyle Educational Session on the Severity of Dysmenorrhea and Premenstrual Syndrome among Nurses Students

Author: Mona Awadhallah Alharbi

International Journal of Novel Research in Healthcare and Nursing

ISSN 2394-7330

Vol. 12, Issue 3, September 2025 - December 2025

Page No: 1-6

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 09-September-2025