Abstract: Background: Helicobacter pylori is one of the most common chronic infections in the world, with a prevalence ranging from 79–90% in low-income countries. The infection is mostly asymptomatic but can manifest as dyspeptic disease, malignant complications such as gastric and esophageal cancer, and non-malignant complications, for example iron-deficiency anemia. These tend to increase the disease burden among persons living in low- and middle-income countries, while it hampers the efforts to meet the sustainable development goals (SDG) for health.
Aim: To determine pattern of HIV infection among persons infected with Helicobacter pylori in a tertiary healthcare institution.
Method: The study assessed the demographic distribution of persons tested for H. pylori in a tertiary healthcare institution within a 1-year period (January – December 2021) in Rivers state University Teaching Hospital. A Rapid diagnostic H. pylori Enzyme-linked immunosorbent assay (ELISA) test kit was used to assess the presence of H. pylori in blood samples collected from 457 persons. HIV tests was conducted from blood samples drawn from each participant using commercially available HIV I/II test kits.
Results: The results showed that 64.8% of the infected persons were female compared to males which made up 35.2% of the infected persons. The H. pylori infection was found to be relatively higher among persons aged 30 – 39 years (44.9%), followed by persons between 40 – 49 years (22.1%) and persons between 50 – 29 years (7.7%). However, the age-group with the lease occurrence of H. pylori infection were persons between 1 – 9 years (2.8%), followed by persons between 10 – 19 years (6.3%) and persons that were 60 years and above (5.9%). There was a 0.7% prevalence of HIV among the persons infected with H. pylori. 1.24% (2/161) of male subjects had HIV compared to 0.34% (1/296) of female subjects with HIV. Among the persons infected with H. pylori, 0.99% (1/101) of persons aged 40 – 49 years had HIV, while 0.97% (2/205) of persons with H. pylori infection aged 30 – 39 years had HIV. The distribution of HIV by demographic characteristics among the persons with H. pylori infection was not statistically significant.
Conclusion: The study showed that the occurrence of HIV infection among persons with H. pylori was relatively low. However, H, pylori infection was found to be higher among females and persons aged between 30 and 49 years old.
Keywords: HIV, Helicobacter pylori, ELISA, Port Harcourt.
Title: Seroprevalence of HIV among persons with Helicobater pylori in a Tertiary Healthcare Institution, Rivers state, Nigeria
Author: Awopeju ATO, Nnokam B, A., Kinako S E.
International Journal of Novel Research in Interdisciplinary Studies
ISSN 2394-9716
Vol. 10, Issue 2, March 2023 - April 2023
Page No: 55-60
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 26-April-2023