Abstract: Background: Ciprofloxacin belongs to the fluoroquinolone class of antibiotics, which are often prescribed to treat various bacterial infections, including those of the respiratory, urinary, and gastrointestinal tracts. Research has shown that Dennettia tripetala contains bioactive compounds which are known to possess strong antioxidant properties Aim: The primary aim of this study was to evaluate the protective effect of Dennettia tripetala (pepper fruit) against ciprofloxacin-induced cardiac and lung damage in albino rats. Methodology: The animals used were grouped into 5 comprising of 5 rats in each group and were acclimatized in a well ventilated iron cage for a period of 14 days prior to the commencement of the experiment. All groups except the baseline control (group 1) received 100mg/kg body weight of ciprofloxacin for 10 days.  Group 2,3 and 4 received additional oral doses of Dennettia tripetala extract of (400, 600, 1000) mg/kg b.wt for 14 days respectively. Group 5 served as the negative control, and received only ciprofloxacin at a dose of 100mg/kg body weight for 10 days. On the last day of treatment, the rats were sacrificed under chloroform anesthesia, the hearts and lungs were carefully excised using a sterile surgical blade. The harvested organs were fixed, histologically processed and stained using H&E staining. Result: The findings suggested that Dennettia tripetala extract possesses significant protective potential, effectively mitigating ciprofloxacin-induced cardiopulmonary damage in albino rats

Keywords: Ciprofloxacin, Dennettia tripetala, Cardiac, Pulmonary, Toxicity, Albino rats.

Title: EVALUATION OF DENNETTIA TRIPETALA (PEPPER FRUIT) ETHANOL EXTRACT AGAINST CIPROFLOXACIN-INDUCED CARDIOPULMONARY DAMAGE IN ALBINO RATS

Author: Nkiruka Millicent Amadi, Theresa Chiamaka Ene, Nonyelum Vivian Anoh

International Journal of Novel Research in Interdisciplinary Studies

ISSN 2394-9716

Vol. 13, Issue 4, July 2026 - August 2026

Page No: 9-17

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 11-August-2026

Abstract: This study investigated the relationship between stakeholders' accountability practices and the administrative effectiveness of secondary school principals in Delta State, Nigeria. Two research questions and one hypothesis guided the study, which adopted an ex-post facto correlational design. From a population of 473 principals and 11,777 teachers in public secondary schools, a sample of 606 respondents (85 principals and 521 teachers) was drawn using a multi-stage/cluster sampling technique. Two researcher-developed instruments — the Stakeholders' Involvement in Accountability Questionnaire (SIAQ) and the Administrative Effectiveness Questionnaire (AEQ) — were used for data collection. Their face and content validity were established by experts in educational administration and in measurement and evaluation at the Faculty of Education, Delta State University, Abraka, while their internal consistency, assessed with Cronbach Alpha, yielded reliability coefficients of 0.81 and 0.78 respectively. Data were analysed using mean and standard deviation, coefficient of determination, and Pearson Product Moment Correlation, with the hypothesis tested at the 0.05 level of significance. Findings showed that stakeholders' involvement in principals' accountability was generally high, and that stakeholders' accountability practices were significantly and positively related to principals' administrative effectiveness (r = .864, p < .05), accounting for 54.2% of the variance in administrative effectiveness. The study concluded that stakeholders' accountability practices are a strong predictor of principals' effective administration of secondary schools, and recommended that the Ministry of Education and school boards institute structured platforms for regular consultation with stakeholders, including parents, community leaders, and alumni, to strengthen transparency and shared responsibility in school administration.

Keywords: Accountability, effective administration, secondary school, stakeholders.

Title: The Role of Stakeholders' Accountability in Enhancing Secondary School Administration

Author: Adugbo, James A., Peretomode, Victor F., Asiyai, Romina I.

International Journal of Novel Research in Interdisciplinary Studies

ISSN 2394-9716

Vol. 13, Issue 4, July 2026 - August 2026

Page No: 1-8

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 31-July-2026