Abstract: Curcubita Maxima plant is widely cultivated from the warm temperate zone to the tropics, mainly for its edible fruit but also for its leaves and seed plus its various medicinal uses and the seeds are diuretic, tonic and vermifuge. This study investigated the curative effect of Curcubita maxima leaf extract on Paracetamol-induced testicular injury. Twenty-four male Wistar rats were grouped into 6 groups with 4 rats in each group. Group 1 received oral normal saline 0.5ml daily throughout the period of the experiment. Groups 2, 3, 4, 5, and 6 received oral Paracetamol 300mg/kg daily from day 1-14. Then from day 15-21, groups 3, 4 and 5 received oral Cucurbita maxima leaf extract 25mg/kg, 50mg/kg and 75mg/kg, respectively, while group 6 received oral Vitamin E 500iu/kg. The Wistar rats were sacrificed following intraperitoneal injection of Thiopentone 50mg/kg. The testes were stained with Haematoxylin and Eosin stain and analyzed using light microscope (X100). The study observed that the testis of group 2 which received Paracetamol showed necrotic interstitial cells and shrunken seminiferous tubules with few luminal spermatozoa in the lumen, while groups 3, 4 and 5 that received Cucurbita maxima leaf extract at different doses showed moderate restoration of the histoarchitexture of interstitial cells and the seminiferous tubule. This study concludes that Cucurbita maxima leaf has the potential to restore the histoarchitexture of the testis following testicular injury caused by Paracetamol overdose.

Keywords: Paracetamol, Cucurbita maxima, Testicular injury, Testis, plant, histoarchitecture.

Title: CURATIVE EFFECT OF CUCURBITA MAXIMA ON PARACETAMOL-INDUCED TESTICULAR INJURY IN ADULT WISTAR RATS

Author: Ifeanacho Ezeteonu Abireh, Chiadikobi Lawrence Ozoemena, Christian Ejuiwa Mba

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 11, Issue 2, March 2024 - April 2024

Page No: 31-37

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 30-April-2024

Abstract: The world's most significant annual legume, groundnut (Arachis hypogaea L.), is primarily farmed for food, animal feed, and oilseed. Three years in a row, the experiment was run at two different locations. Three replicates were used in the split-spilt plot design of the experiment. Pre-tagged samples of five plants per plot were used to record data on growth and yield parameters such as days to 50% emergence, days to 75% emergence, 50% flowering, days to 75% maturity, stand count at maturity, mature pod/plant, branch number/plant, dry pod yield, shelling%, 100 seed weight, and pest and disease reaction. Plant spacing and variety had no discernible effects on the phenologcal phases of groundnut growth at either site. The quantity of ripe pods per plant and the weight of the seeds were significantly impacted by variabilities. While NC-343 had a larger seed weight at both Babile and Goffa, the variety Werer 961 had more pods. Only the stand count at maturity was considerably impacted by inter-row spacing, but both SCAM and MPPP were impacted by intra-row spacing. At both sites, a high population density was noted with smaller intrarow and interrow separations of 10 cm and 50 cm, respectively, and declined consistently with increasing inter and intra spacing, although MPPP fell inconsistently with increased intra spacing. For both locations, there was no statistically significant interaction between the inter- and intra-spacing. Groundnut grain yield was highly influenced by the year, variety, and intra- and inter-spacing. In both areas, a higher yield was obtained during the 2011 cropping season. Though there were minor variations, the three-year production from Goffa was largely excellent, and 2012 was not good for the Babile location. At Babile, the yield was drastically decreased (514 kg/ha) as a result of irregular and little rainfall. There was shown to be a statistically significant (P<0.05) variation in grain yield between the two kinds. While NC-343 produced 1829 kg/ha in Goffa and 1432 kg/ha at Babile, Werer 963 produced an average grain yield of 2259 kg/ha at Goffa and 1630 kg/ha at Babile, respectively.

Keywords: Plant Spacing, Population, Density, Yield, Inter-Row, Intra-Row.

Title: Effects of Plant Spacing and Population Density on Growth, Yield and Yield Attributes of Groundnut

Author: Tamiru Dejen, Brehanu Woldu, Fikeremariam Tegegn, Getnet Adugna

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 11, Issue 2, March 2024 - April 2024

Page No: 26-30

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 25-March-2024

Abstract: The sowing date is one of the more important factors that determines the yield of irrigated wheat. This experiment was conducted to find out the proper sowing time for low-land irrigated wheat varieties under the irrigation conditions of Middle Awash, Ethiopia. The experiment was laid out in an RCBD design with three replications and seven sowing dates (1^st October, 15^th October, 30^th October, 15^th November, 30^th November, 15^th December, and 30^th December), and the Gambo wheat variety was used as the test crop for the experiment as treatments. Productive tiller/plant height Grain/spike, biomass yield t/ha, grain yield kg/ha, 1000 seed weight, straw yield, and harvest index were significantly affected by the treatment. However, total tiller/plant and spike length were not significantly affected by the treatment. The highest biomass yield (16.1 t ha^-1) was obtained when the crop was sown on 15^th October it was at par with 3858.1 kg ha-1 and 3674.6 kg ha^-1 obtained from 1^st October and 15^th November respectively. The lowest biomass yield (5.1 t ha^-1) was recorded in the case of late sowing, i.e., December 15^th, which was on par with December 30^th. The highest grain yield (3881.2 kg ha^-1) was obtained when the crop was sown on 1^st October it was on par with 3858.1 kgha^-1 and 3674.6 kg ha^-1 obtained from 15^th October and 15^th November respectively. The lowest grain yield (559.3 kg ha^-1) was recorded in case of late sowing, i.e. 15^th December, which was on par with 30^th December.

Keywords: Biomass yield; Grain yield; Sowing date; Straw yield; Tiller; Wheat.

Title: Effects of sowing date on wheat productivity under irrigated condition, Middle Awash, Ethiopia

Author: Tamiru Dejen, Fikeremariam Tegegn, Mekuria Bekele

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 11, Issue 2, March 2024 - April 2024

Page No: 21-25

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 18-March-2024

Abstract: Reactive oxygen species (ROS), unavoidable by products of aerobic metabolism, are known to cause oxidative damage to cells and molecules. This in turn is widely accepted as a fundamental determinant of both life and life span. Harman was the first to put forward that the damaging effects of ROS may play a key role in the mechanism of aging. Genetic studies of such abstractedly related species of Caenorhabditis elegans, Drosophila melanogaster, and mice support this hypothesis. However, ROS are not only a cause of structural damage, but also physiologically signally processes. Abnormally high levels of ROS may therefore lead to dysregualtion of redox-sensitive signaling pathways. This paper gives an overview of the positive and negative functions of reactive oxygen species, the oxidative stress, rate of living and ROS signaling theory of aging, mechanism of aging, effect of oxidative stress and the interaction of aging and age-related disease and the effect of antioxidants supplementation on aging and longevity.

Keywords: Reactive oxygen species (ROS), longevity, oxidative stress, antioxidants and supplementation.

Title: OXIDATIVE STRESS AND LONGEVITY

Author: Yocy Yohana Izam, Kennedy Iliya Amagon, Nenman Noel Wannang

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 11, Issue 2, March 2024 - April 2024

Page No: 11-20

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 09-March-2024

Abstract: The genus Kazachstania Zubkova sensu Kurtzman (2003) was first introduced as a monotypic genus including Kazachstania viticola Zubkova (1971). Later, a large number of species were accommodated to the genus. However, the phylogenetic analyses indicated that the genus was extremely diverse, since the species concerned showed very long branches in the phylogenetic trees. The calculated pair-wise sequence similarities of K. viticola were quite low (88.8 - 95.2%) to the remaining 30 species. The phylogenetic data obtained indicated that the genus formed the so-called Kazachstania complex, which was subdivided into 10 taxa at the generic level, as found in the genus Wickerhamomyces Kurtzman et al. (2008) as well as the genus Schizosaccharomyces Lindner (1893) sensu Kurtzman et Robnett (1991).

Keywords: Kazachstania viticola; Vanderwaltomyces africanus; Arxiozyma telluris; Pachytichospora transvaalensis; Sinensiomyces sinensis; Baiomyces aquaticus; Mikataea zonata; Neoyamazakia rossinii; Capriottia servatii; Neovaughania barnettii.

Title: The Subdivision of the Genus Kazachstania Zubkova (1971) sensu Kurtzman (2003) (Sacchromycetaceae)

Author: Yuzo Yamada, Taweesak Malimas, Huong Thi Lan Vu, Pattaraporn Yukphan, Somboon Tanasupawat

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 11, Issue 2, March 2024 - April 2024

Page No: 1-10

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 5-March-2024