Abstract: Integrating digital tools in STEM education can transform traditional teaching methods and provide enhanced learning experiences. This paper explores the significance of empowering STEM educators through the adoption and effective utilization of digital tools in teaching and learning STEM concepts. The study examines various digital resources, including interactive simulations, virtual labs, Google Classroom, virtual field trips, coding platforms, robotic and engineering kits, Mathematics learning tools, Game-based learning platforms, online learning platforms, and 3D modeling (DT), and their impact on teaching practices and students’ engagement. By leveraging tools, STEM educators can create dynamic, immersive learning environments that foster critical thinking, problem-solving, and collaborative skills. This paper highlights best practices for integrating these technologies into curricula, addressing challenges such as digital literacy and access to resources. The findings from the literature suggest that when STEM educators are equipped with the appropriate digital tools and training, they are better positioned to inspire and motivate students, have access to global knowledge, increase students’ engagement, and ultimately contribute to a more robust, dynamic, and innovative STEM education landscape.

Keywords: Digital Literacy, Digital tools, Empowering, Professional Development, STEM Educator, Students’ engagement, Teaching Practices.

Title: Empowering STEM Educators: Leveraging Digital Tools for Enhanced Teaching

Author: Aminat Aderonke Agoro, Ikeoluwa Folasade Adeoye, Kikelomo Olajumoke Alayande

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 12, Issue 2, March 2025 - April 2025

Page No: 58-67

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 16-April-2025

Abstract: The main purpose of this study was to Assessment of fish handling practices in Mogadishu fish markets and suggestions for improvement, Somalia. The research design used was descriptive research also the target population of this study were 90 respondents. The researcher selected 73 with the help of Slovene’s formula. The research instrument used was questionnaire to collect the data of the respondents and the sample procedure this study was employed purposive sampling that is part from non-probability sampling techniques. purposive sampling was used to select a participant from the target population. The required information for this study was gathering through questionnaire. And then the data was analyzed by using (SPSS); the findings of the study indicates that the majority of the respondents disagreed that fish handling have a negative impact on Mogadishu fish markets. The researchers recommended: Improve Market Premises Cleanliness such as regularly clean and disinfect floors, walls, and equipment in the fish markets to maintain a hygienic environment, Implement Cold Chain Management such as ensure the availability of sufficient ice or refrigeration facilities in the fish markets to maintain proper temperature control throughout the supply chain, Training on Fish Quality Assessment such as conduct training programs for fish market workers to educate them on how to assess fish quality based on appearance, texture, and odor, Strengthen Regulations such as review and update existing regulations related to fish handling practices in Mogadishu fish markets to align with international standards and best practices.

Keywords: fish handling, market hygiene, cold chain management, quality assessment, regulations, Mogadishu fish markets.

Title: ASSESSMENT OF FISH HANDLING PRACTICES IN MOGADISHU FISH MARKETS AND SUGGESTIONS FOR IMPROVEMENT

Author: Sakariye Ahmed Hashi, MOHAMED ABDISAMED ABDIRAHMAN, HASSAN NUR SHARAWE, ABDULLAHI SHEIKH HASSAN, ABDULLAHI HASSAN ABDULLAHI, MARIA ABDULLAHI MOHAMUD

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 12, Issue 2, March 2025 - April 2025

Page No: 47-57

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 09-April-2025

Abstract: Processing is important to eliminate harmful microorganisms and extend the shelf life of food. Due to the application of heat during processing and a longer storage period, there is the possibility of nutrient loss. Pepper (Capsicum spp) and tomato (Lycopersicum esculentum) are antioxidant-rich vegetables known for several pharmacological benefits. The effect of processing and storage on the functionality of sauce produced from pepper and tomato was investigated in this study. The sauce was processed under heat (temperature maintained between 95℃ to 98℃ for 10 mins) and stored in a glass jar for different periods (1-3 months). Nutritional compositions, in vitro antioxidant properties, and phenolic characterization of the samples were evaluated in comparison with a fresh sample. The samples, especially up to 2-month storage, did not significantly differ at p < 0.05 in antioxidant parameters and some nutritional content when compared to the fresh sample. The HPLC characterization of the sauce revealed the presence of carotenoids in both the fresh and stored sauces, with a better concentration in one of the stored sauces. Capasanthin was the highest compound quantified in the fresh and 1-3 months stored sauce (2.80 mg/g, 3.74 mg/g, 4.83 mg/g, 4.08 mg/g, respectively). Processing did not alter the antioxidant and nutritional compositions, but storing for more than 2 months could cause a decline in some of its nutritional value.

Keywords: Antioxidant, Glass jar, Heat application, Nutrition, Storage.

Title: Effects of processing and storage on the nutritional composition of sauces made from two pepper varieties (Capsicum chinense and Capsicum annuum) and tomato (Lycopersicum esculentum)

Author: Oluwakemi V. Adeleke, Olorunfemi R. Molehin, Toyosi E. Kuti, Olumide O. Adu

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 12, Issue 2, March 2025 - April 2025

Page No: 40-46

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 03-April-2025

Abstract: The highly adaptive cellular response of Mycobacterium tuberculosis to various antibiotics, combined with the high costs of clinical trials, hamper the development of novel antimicrobial agents with improved efficacy and safety. Subsequently, in silico drug screening methods are increasingly used in drug discovery and development and have proven useful for predicting the pharmacokinetics, toxicities, and targets of prospective new antimicrobial agents. In this investigation, we employed a reverse target fishing approach to identify potential hit targets and explore their interactions between M. tuberculosis and a promising new antituberculosis compound. Two of the four identified targets, Cyp130 and 1SFR, were strongly proposed as optimal drug targets for dormant M. tuberculosis, with Cyp130 exhibiting the highest binding affinity. The metabolic pathways associated with the selected target proteins were compared to previously published molecular mechanisms of Cyp130 in M. tuberculosis, confirming disruptions in the metabolism of proteins, cell wall components, and DNA. We also detailed the specific steps within these pathways that are inhibited and elaborated on the role of Cyp130 against dormant M. tuberculosis. This compound has previously shown promising in vitro safety and good oral bioavailability, both of which were supported by this in silico study. The pharmacokinetic properties and toxicity of the compound were predicted and evaluated using the online tools pkCSM and SwissADME, along with Discovery Studio software, further supporting its safety and bioavailability as an antimycobacterial agent.

Keywords: Mycobacterium tuberculosis, phytocompounds, mondoro myristica, ADMET.

Title: Insilico studies of therapeutic agents in Phytocompounds obtained from mondoro myristica (African nutmeg) against Mycobacterium tuberculosis

Author: Dearsly, Emmanuel Markus; Eze, Kingsley Chijioke; Oshatuyi, Olukayode; Shaibu, Aisha Oiza; Nwosu, Uzoamaka Amararachi; Mmadu, Michael Ezenwa

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 12, Issue 2, March 2025 - April 2025

Page No: 23-39

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 17-March-2025

Abstract: Sorghum (Sorghum bicolor) is a vital cereal crop, particularly for food security in arid and semi-arid regions. This study investigates the adoption determinants of improved sorghum varieties (Assosa-1 and Adukara) by smallholder farmers in the Metekel Zone, Benishangul-Gumuz Region, Northwestern Ethiopia. Employing a double-hurdle econometric model, the research analyzes primary and secondary data from 142 households sampled through multistage probability techniques. The findings reveal significant factors influencing both the decision to adopt and the extent of adoption, including access to credit, market access, proximity to cooperatives, sorghum yield, and total sorghum sold.

Male-headed households, closer distance to cooperatives, and access to financial and extension services were positively correlated with adoption levels. However, challenges such as limited access to improved seeds, financial constraints, and inadequate market infrastructure hinder broader adoption. The study underscores the importance of addressing these barriers through targeted policy interventions to enhance sorghum productivity and farmer livelihoods. The findings contribute to understanding technology adoption dynamics in humid lowland agroecologies, offering insights for agricultural development and food security strategies.

Keywords: Adoption, Improved Sorghum Variety, Metekel Zone, Double Hurdle Model.

Title: Determinants of Adopting of Improved Sorghum Variety (Assosa_1 & Adukara) Under Smallholder Farmers in Metekel Zone, Benishangul Gumuz Region, North Western Ethiopia

Author: Belete Woundefiraw, Welay Tesfay

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 12, Issue 2, March 2025 - April 2025

Page No: 9-22

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 10-March-2025

Abstract: Novel target compound, 2-(3-(5-cyano-6-oxo-4-phenyl-1,6-dihydropyridin-2-yl)phenoxy)acetic acid 2, was synthesized and evaluated for its anti-inflammatory activity using carrageenan-induced rat paw edema method in comparison with the selective COX-2 inhibitor, celecoxib. The results suggested that compound 2 proved good potency with edema inhibition rates of 22.28 and 25.23% at the third and fifth hours, respectively.  More SAR study and optimization are warranted for compound 2, which has the potential to be employed as oral anti-inflammatory drugs.

Keywords: Cyanopyridine; Anti-inflammatory; COX; Cyclooxygenase enzymes; Selective COX-2.

Title: Synthesis, and biological evaluation of novel 2-(3-(5-cyano-6-oxo-4-phenyl-1,6-dihydropyridin-2-yl)phenoxy)acetic acid as potential in vivo anti-inflammatory agent

Author: Alshimaa Kh. M. Ahmed, Mamdouh F. A. Mohamed, Eman A. M. Beshr

International Journal of Novel Research in Life Sciences                                                   

ISSN 2394-966X

Vol. 12, Issue 2, March 2025 - April 2025

Page No: 1-8

Novelty Journals

Website: www.noveltyjournals.com

Published Date: 05-March-2025